Pluto in 6th could suggest someone whose job is more than just a job. They go the extra extra extra mile.If a Pluto in 6th person is in a job they don't feel passionate about,it can be a life crisis. Everything can seem grey because of the job
If Pluto in 6th person has a job they love. They become so enwrapped in that job, their life starts to revolve around it. Pluto in 6th transits do that too.
With Pluto in 6th, finding their purpose in life will become a preoccupation and obsession- especially if Pluto is in Scorpio. Something they can sink their teeth into. Otherwise, nothing else works.
Pluto in 6th may go for the types of jobs that have no " clock out" to them. These jobs are high adrenalin go, go, go types.
If I were a Pluto in 6th,I would look for a job that has my heart skip a beat. And turn that job into a career. Because it will by default.
Many go the entrepreneurial route when older or look to be their own boss(like Mars in 6th).
Pluto in 6th guy I know drives an ambulance. He is never available and lives to work(the other danger with this position)