Okay. MOON-MERCURY-VENUS conjunct with SUN-MARS conjunct, 0º, but not aspecting each other. VERTEX conjunct DSC.Got it.
SATURN conjunct PLUTO can be fine, depending upon how the energy is channelled. URANUS opposite the MOON-MERCURY-VENUS indicates an unlikelihood that this relationship will ever be committed, and or conventional. It's subject to extreme upheaval and volatility, namely due to moodiness and fluctuating feeling.
SATURN on the homicidal degree of 19º Libra, for example, can show some potentially violent karma to sort through. But not always; it's not that configured: SATURN and PLUTO are not THAT close together; a 6º conjunction in a composite of generational points isn't that tight.
VENUS-MOON-MERCURY is a very nice friendship influence. The lack of VENUS to MARS can show it lacks a romantic spark, however. Same for the SUN and MOON lacking an aspect; there's a basic disconnect between the identity of the relationship and its emotional core.
The fact that cSUN is the 7R and links to the 3R (MARS) shows that there's a drive for communication or sharing thoughts and ideas. There's a dynamic, intellectual connexion.
The 8H is represented however, with the conjunction of MERCURY to MOON and VENUS. Clearly the potential for an undercurrent of a sexual nature, which is likely to have a drive to be committed and deeply emotional: 4H.
You see the problem.
There's a natural drive to settle down and create a home and family, but 10H cURA creates a constant opposite drive towards separation and upheaval.
Why?
We'd have to look at who might be expressing the Uranian energy, (what might be hitting the cURA) and how that point is expressing itself natally. As well as examining the position of both nURA points to get an idea of what may be driving the individual(s) towards freedom and away from commitment.
JUNO is close enough to the POF, showing that the relationship can be of general benefit, likely regarding improving everyday life.
The real issue is going to be the cURA opposite cMOON-MERC-VENUS. This may be as simple as 'our dedication to our careers doesn't let us put down roots together and build a family,' as cURA's disposited by cJUPITER right on the MC, 2º.
That's a cursory look.