Yes, we've heard that the 2nd shot of vaccine can give harsher side-effects than the 1st. The doctors say that's a GOOD sign that your body is responding favorably to gain its immunity.
Have to be careful if you take the ibuprofen.. Can cause bleeding in the stomach and small intestines if you have inflammation or acid problems. Seniors are warned not to take those N-SAIDS, for that reason.
Acetaminophen (tylenol) works especially well for injection-site soreness, body-aches, any headache, and lowering fever. Heard that the side-effects (IF you get them) last for just a day.